| DATE | HOME | SCORE | AWAY | |||
|---|---|---|---|---|---|---|
| 22/10/2021 |  | TORINO | 3 - 2 | GENOA |  | |
| 22/10/2021 |  | SAMPDORIA | 2 - 1 | SPEZIA |  | |
| 23/10/2021 |  | SALERNITANA | 2 - 4 | EMPOLI |  | |
| 23/10/2021 |  | SASSUOLO | 3 - 1 | VENEZIA |  | |
| 23/10/2021 |  | BOLOGNA | 2 - 4 | AC MILAN |  | |
| 24/10/2021 |  | ATALANTA | 1 - 1 | UDINESE |  | |
| 24/10/2021 |  | FIORENTINA | 3 - 0 | CAGLIARI |  | |
| 24/10/2021 |  | HELLAS VERONA | 4 - 1 | LAZIO |  | |
| 24/10/2021 |  | ROMA | 0 - 0 | NAPOLI |  | |
| 24/10/2021 |  | INTER MILAN | 1 - 1 | JUVENTUS |  |
