| DATE | HOME | SCORE | AWAY | |||
|---|---|---|---|---|---|---|
| 16/10/2021 |  | SPEZIA | 2 - 1 | SALERNITANA |  | |
| 16/10/2021 |  | LAZIO | 3 - 1 | INTER MILAN |  | |
| 16/10/2021 |  | AC MILAN | 3 - 2 | HELLAS VERONA |  | |
| 17/10/2021 |  | CAGLIARI | 3 - 1 | SAMPDORIA |  | |
| 17/10/2021 |  | EMPOLI | 1 - 4 | ATALANTA |  | |
| 17/10/2021 |  | GENOA | 2 - 2 | SASSUOLO |  | |
| 17/10/2021 |  | UDINESE | 1 - 1 | BOLOGNA |  | |
| 17/10/2021 |  | NAPOLI | 1 - 0 | TORINO |  | |
| 17/10/2021 |  | JUVENTUS | 1 - 0 | ROMA |  | |
| 18/10/2021 |  | VENEZIA | 1 - 0 | FIORENTINA |  |
