| DATE | HOME | SCORE | AWAY | ||||
| 26.10.2005 |  | REAL BETIS | 2-3 | VILLARREAL |  | ||
| 26.10.2005 |  | MALLORCA | 1-0 | CELTA DE VIGO |  | ||
| 26.10.2005 |  | OSASUNA | 3-2 | ATHLETIC BILBAO |  | ||
| 26.10.2005 |  | BARCELONA | 2-0 | MÁLAGA |  | ||
| 26.10.2005 |  | DEPORTIVO LA CORUÑA | 3-1 | REAL MADRID |  | ||
| 27.10.2005 |  | REAL ZARAGOZA | 1-1 | RACING SANTANDER |  | ||
| 27.10.2005 |  | REAL SOCIEDAD | 3-0 | GETAFE |  | ||
| 27.10.2005 |  | DEPORTIVO ALAVÉS | 1-1 | ESPANYOL |  | ||
| 27.10.2005 |  | ATLÉTICO MADRID | 3-0 | CÁDIZ |  | ||
| 27.10.2005 |  | VALENCIA | 0-2 | SEVILLA |  |
