| DATE | HOME | SCORE | AWAY | |||
|---|---|---|---|---|---|---|
| 05/11/2021 |  | MAINZ 05 | 1 - 1 | BORUSSIA M'GLADBACH |  | |
| 06/11/2021 |  | BAYERN MÜNCHEN | 2 - 1 | FREIBURG |  | |
| 06/11/2021 |  | WOLFSBURG | 1 - 0 | AUGSBURG |  | |
| 06/11/2021 |  | STUTTGART | 0 - 1 | ARMINIA BIELEFELD |  | |
| 06/11/2021 |  | BOCHUM | 2 - 0 | HOFFENHEIM |  | |
| 06/11/2021 |  | RB LEIPZIG | 2 - 1 | BORUSSIA DORTMUND |  | |
| 07/11/2021 |  | HERTHA BERLIN | 1 - 1 | LEVERKUSEN |  | |
| 07/11/2021 |  | KÖLN | 2 - 2 | UNION BERLIN |  | |
| 07/11/2021 |  | GREUTHER FÜRTH | 1 - 2 | EINTRACHT FRANKFURT |  | |
 | |
