| DATE | HOME | SCORE | AWAY | |||
|---|---|---|---|---|---|---|
| 22/10/2021 |  | SAINT-ÉTIENNE | 2 - 2 | ANGERS |  | |
| 23/10/2021 |  | NANTES | 2 - 1 | CLERMONT |  | |
| 23/10/2021 |  | LOSC LILLE | 1 - 1 | STADE BRESTOIS |  | |
| 24/10/2021 |  | OGC NICE | 3 - 2 | OLYMPIQUE LYONNAIS |  | |
| 24/10/2021 |  | RC LENS | 4 - 1 | METZ |  | |
| 24/10/2021 |  | LORIENT | 1 - 1 | BORDEAUX |  | |
| 24/10/2021 |  | STADE DE REIMS | 1 - 2 | TROYES |  | |
| 24/10/2021 |  | STADE RENNAIS | 1 - 0 | STRASBOURG |  | |
| 24/10/2021 |  | MONACO | 3 - 1 | MONTPELLIER |  | |
| 24/10/2021 |  | MARSEILLE | 0 - 0 | PARIS SAINT-GERMAIN |  |
