| DATE | HOME | SCORE | AWAY | |||
|---|---|---|---|---|---|---|
| 26/11/2021 |  | ATHLETIC BILBAO | 2 - 2 | GRANADA |  | |
| 27/11/2021 |  | DEPORTIVO ALAVÉS | 1 - 2 | CELTA DE VIGO |  | |
| 27/11/2021 |  | VALENCIA | 1 - 1 | RAYO VALLECANO |  | |
| 27/11/2021 |  | MALLORCA | 0 - 0 | GETAFE |  | |
| 27/11/2021 |  | VILLARREAL | 1 - 3 | BARCELONA |  | |
| 28/11/2021 |  | REAL BETIS | 3 - 1 | LEVANTE |  | |
| 28/11/2021 |  | ESPANYOL | 1 - 0 | REAL SOCIEDAD |  | |
| 28/11/2021 |  | CÁDIZ | 1 - 4 | ATLÉTICO MADRID |  | |
| 28/11/2021 |  | REAL MADRID | 2 - 1 | SEVILLA |  | |
| 29/11/2021 |  | OSASUNA | 1 - 1 | ELCHE |  |
