| DATE | HOME | SCORE | AWAY | |||
|---|---|---|---|---|---|---|
| 27/08/2021 |  | MALLORCA | 1 - 0 | ESPANYOL |  | |
| 27/08/2021 |  | VALENCIA | 3 - 0 | DEPORTIVO ALAVÉS |  | |
| 28/08/2021 |  | CELTA DE VIGO | 0 - 1 | ATHLETIC BILBAO |  | |
| 28/08/2021 |  | REAL SOCIEDAD | 1 - 0 | LEVANTE |  | |
| 28/08/2021 |  | ELCHE | 1 - 1 | SEVILLA |  | |
| 28/08/2021 |  | REAL BETIS | 0 - 1 | REAL MADRID |  | |
| 29/08/2021 |  | BARCELONA | 2 - 1 | GETAFE |  | |
| 29/08/2021 |  | CÁDIZ | 2 - 3 | OSASUNA |  | |
| 29/08/2021 |  | RAYO VALLECANO | 4 - 0 | GRANADA |  | |
| 29/08/2021 |  | ATLÉTICO MADRID | 2 - 2 | VILLARREAL |  |
